Current Vacancies
Structural Biologists (Ref SB-10)
10/05/2010
Astex Therapeutics is a world leader in fragment-based drug discovery. The company has a strong commitment to X-ray crystallography – all our projects are based on a detailed understanding of protein: ligand interactions and thus structural biology plays a major role in drug design within the company.
We have opportunities for both permanent and post-doctoral structural biologists to join Astex and to influence our discovery and development projects. The successful applicants will have a PhD in Structural Biology, and will have experience in the areas of molecular biology, protein production and crystallography. A knowledge of, and an interest in protein-ligand interactions and drug design would be advantageous, as would be an interest in method development for high throughput crystallography.
Kindly send your CV and a cover letter outlining your experience relevant to this role by email to the below address or by post.
Medicinal Chemists (Ref MC-10)
14/04/2010
Cambridge Science Park
Several opportunities exist for synthetic Medicinal Chemists to work on FBDD in close collaboration with Computational Chemistry, Structural Biology, Biology and ADME. The candidates need to be highly rigorous scientifically and able to challenge and stimulate like-minded colleagues at Astex. Experience in structure-based drug design is desirable but not essential. An outstanding knowledge and track record in synthetic organic chemistry, with significant practical laboratory experience is required.
Several opportunities exist for synthetic medicinal chemists to work on FBDD in close collaboration with computational chemistry, structural biology, biology and ADME. The candidates need to be highly rigorous scientifically and able to challenge and stimulate like-minded colleagues at Astex. Experience in structure-based drug design is desirable but not essential. An outstanding knowledge and track record in synthetic organic chemistry, with significant practical laboratory experience is required.
Essential:
The roles will be primarily laboratory-based, so current knowledge and practical experience in organic synthesis is essential;
Proven record of scientific excellence e.g. through inventorship and/or publication;
Ability scientifically to challenge and stimulate like-minded colleagues at Astex;
Commitment to advancing the field of FBDD and SBDD;
Drive for results and ability to adapt in a fast-paced research environment.
Desirable:
Significant experience in SBDD;
Experience in the use of computational modelling techniques in drug design;
Demonstrated ability to collaborate across scientific disciplines.
Candidates should have a PhD/PostDoc or be a Graduate with several years drug discovery experience with an aim for scientific career development within a laboratory environment.
Salaries and benefits package are highly competitive to ensure we attract, motivate and retain the best candidates. Please send your application to:
Human Resources
Astex Therapeutics Ltd
436 Cambridge Science Park
Milton Road
Cambridge
CB4 0QA
UK
Or apply by e-mail to: HR@astex-therapeutics.com
Please note that Astex is unable to accept speculative applications for studentships or other internships via these contact addresses.