Events and Presentations

22-26 October 2007
AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
San Francisco
presenting

• Comparison of the Pharmacological Profile of AT7519 in Solid Tumour and Haematological Cell Lines

8-11 December 2007
The American Society of Hematology 49th Annual Meeting and Exposition
Atlanta, Georgia
presenting

• A Phase I trial of AT9283, a multitargeted kinase inhibitor in patients with refractory hematological malignancies
• AT9283, a potent inhibitor of JAK2 is active in JAK2 V617F MPD models
• AT7519, a potent CDK inhibitor is active in leukemia models and primary CLL patient samples

6 February 2008
DMDG Spring Meeting: “Discovery and development of new therapies for cancer - a DMPK perspective.”
Cambridge
Astex hosting

11-13 Februray 2008
BIO CEO & Investor Conference
New York
presenting

18-20 February 2008
Fragment-based Lead Discovery Conference 2008
San Diego
presenting

10-12 March 2008
Informa Life Science 7th Annual Protein Kinases Conference
Berlin
presenting

29 March-3 April 2008
2008 Keystone Symposium Computer-Aided Drug Design
Colorado
presenting

7-9 April 2008
Bio-Europe Spring
Madrid
presenting

12-16 April 2008
American Association for Cancer Research (AACR) Annual Meeting 2008
San Diego, CA
presenting

• AT9283, a potent inhibitor of Bcr-Abl T315I, is active in CML models
• Development of inhibitors of the fibroblast growth factor receptor (FGFr) kinase using a fragment based approach

21-22 April 2008
Proteinase 2008 From Molecules to Medicines
London
presenting

28-29 April 2008
CHI Drug Discovery Chemistry
San Diego
presenting

7-9 May 2008
ERBI's 10th Anniversary Cambridge BioPartnering Exchange
Cambridge
presenting

19-22 May 2008
Informa's Annual InfoTech for Pharma and Biotech
Basel
presenting

30 May-3 June 2008
44th ASCO Annual Meeting
Chicago
presenting

16-17 September 2008
Informa conference on Structure based Drug Design
Budapest, Hungary
presenting

9 October 2008
Cutting Edge Approaches to Drug Design
London
presenting